abstract |
[PROBLEMS] To provide a compound having SGLT1 and/or SGLT2 inhibiting potency that can be used as a preventive or therapeutic agent for diabetes, postprandial hyperglycemia, impaired glucose tolerance, diabetic complication, obesity, etc. [MEANS FOR SOLVING PROBLEMS] There are provided 1-substituted-7-(β-D-glycopyranosyloxy)(aza)indole compounds of the general formula (I), prodrugs or pharmacologically acceptable salts thereof, and hydrates or solvates thereof. [Chemical formula 1] (I) wherein R1 is a halogen atom, etc.; n is an integer of 0 to 3; R2 is a halogen atom, etc.; X is a nitrogen atom or carbon atom having a hydrogen atom, etc. bonded thereto; Q is an alkenylene group or alkylene group optionally having an oxygen atom or sulfur atom in its chain; and A is an optionally substituted aryl or heteroaryl group. |