| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f40003f229e7c11b2b2ec1e03f5024a0 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-404
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-426
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1211
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-426 |
| filingDate |
2006-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_483f1426311d6225beeded9b1223fae9 |
| publicationDate |
2007-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1845094-A1 |
| titleOfInvention |
Method of tumor suppression and evaluation of anticancer agent based on gsk3 beta inhibitory effect |
| abstract |
The present invention provides a novel means for cancer treatment and cancer diagnosis by elucidating that glycogen synthase kinase 3β (GSK3β) is involved in the survival and/or the proliferation of cancer cells. Specifically, the present invention relates to: a method for suppressing the survival and/or the proliferation of cancer cells through inhibition of GSK3β expression or inhibition of the activity of this enzyme (GSK3β) activated via phosphorylation of GSK3β tyrosine residue at position 216; and development of novel anticancer agents and a method for evaluating anticancer agents based on the inhibitory effect. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011250584-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104698188-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2086555-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3187495-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8957103-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2010333082-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11045449-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9068231-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011073091-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023060226-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012084683-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2338486-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2474541-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2086555-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017027984-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9364459-B2 |
| priorityDate |
2005-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |