http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1842922-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c16d2144a81bfa32a665dca1e93c3d37 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2537-143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2527-125 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6832 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6848 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2006-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d2ee3370cac9ef2517b26ef3d02dd74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f81dc12c8a728f94a51cd808d03587a4 |
publicationDate | 2007-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1842922-A1 |
titleOfInvention | Method of increasing specificity of nucleic acid hybridization using zwitterionic compound |
abstract | A method of increasing the specificity of nucleic acid hybridization, comprising hybridizing nucleic acid in a solution containing a zwitterionic compound selected from the group consisting of 3-(cyclohexylamino)-1-propanesulfonic acid (CAPS), 3-[(3-cholamidopropyl)dimethylammonio]-1-propane sulfonate (CHAPS), 3-(cyclohexylamino)-2-hydroxy-1-propane sulfonate (CAPSO), and 2-(cyclohexylamino)ethane sulfonate (CHES) is provided. The method allows a reduction in the yield of non-specific hybridization products in multiplex PCRs while maintaining the yield of target hybridization products, thereby increasing the specificity of nucleic acid hybridization. Thus, the method can be effectively used for identification of specific pathogens, diagnosis of genetic diseases, analysis of gene sequences, and so on. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10378050-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9914964-B2 |
priorityDate | 2006-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 88.