http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1842560-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_67f8f7c227a5280128c81dad369fdf44 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 |
| filingDate | 2005-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_426020b03d8076f48d320b7423ef7b18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c31c37fb6c4fe6fce7948196ccf46a9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b909a673bfd34f1ee514f9bb01b8540e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1d9c999bb7f02a0554de97f60bc95c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a34f65cea6d834a91ae6b2125941766a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db4305dc1a10babf1d53b5d77dd5b61e |
| publicationDate | 2007-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1842560-A1 |
| titleOfInvention | A high-intensity focused ultrasound adjuvant and the screening method thereof |
| abstract | The present invention discloses an enhancement agent for high intensity focused ultrasound (HIFU) treatment, which is administered to a patient before HIFU treatment and can reduce the level of EEF at the target location to be treated with HIFU. EEF is presented by the expression: EEF = ηPt / v (unit: J/mm 3 ), and refers to the HIFU energy needed to effectively treat a tumor per unit volume of the tumor, wherein, η=0.7; P refers to the total acoustic power of HIFU source (unit: W); t refers to the total time of HIFU treatment (unit: s); V refers to the volume of HIFU-induced lesions (unit: mm 3 ). If the amount of EEF at the target location before administration of the enhancement agent is defined as EEF (base) and the amount of EEF at the target location after administration of the enhancement agent is defined as EEF (measurement) , the ratio between EEF (base) and EEF (measurement) is more than 1, preferably more than 2, and more preferably over 4. The use of the enhancement agent for HIFU treatment of the present invention makes it possible to treat deep-seated tumors. In addition, patients with hepatic tumors can be effectively treated without removal of ribs. Accordingly, the present invention discloses methods for increasing acoustic energy deposition at target location during HIFU treatment and screening the enhancement agents for HIFU treatment. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IT-201900025303-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1847275-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1847275-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IT-201900025306-A1 |
| priorityDate | 2005-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 98.