| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dfd617dc43a4c986d2dd81e4cb39d9dd |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-916
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-9125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-07049 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99 |
| filingDate |
2005-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b27b8ad90d8e9b5441b367ce86b02229
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9136429969b927fe1c2483f0cf6cfcdc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d006faf1ec8f6e2164bb299538dcef43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e84a32021eea0b76f4bc37d36d0d76e2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2907793c9282ee33ad80ab0d5ceb85d |
| publicationDate |
2007-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1840215-A1 |
| titleOfInvention |
Method of inhibiting telomerase activity and inhibitor |
| abstract |
[PROBLEMS] To find out proteins involved in regulation of telomerase activity and to provide a method of inhibiting telomerase activity and a method of enabling the prevention and/or treatment of diseases attributable to the enhanced telomerase activity. n [MEANS FOR SOLVING PROBLEMS] A method of enhancing degradation of telomerase, comprising inhibiting the binding of TERT (telomerase catalytic subunit) to USP21, the binding of NEDD8-conjugated TERT to USP21, or the NEDD8 deconjugation by USP21 from NEDD8-conjugated TERT; a method of inhibiting telomerase activity, comprising using the method of enhancing the degradation; a method of identifying a compound that inhibits the binding or the NEDD8 deconjugation; an agent for inhibiting telomerase activity, comprising the compound; an agent for preventing and/or treating diseases attributable to the enhanced telomerase activity is described and includes, comprising the inhibitory agent; a method of preventing and/or treating the diseases, comprising using the inhibition method or the inhibitory agent a reagent kit. |
| priorityDate |
2004-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |