abstract |
This invention features a therapeutic composition for the treatment of an inflammatory or immune-mediated disease condition, the therapeutic composition comprising an isolated Yatapoxvirus cytokine inhibitor protein formulated in a pharmaceutically acceptable vehicle, a method of modulating cytokine function in a cell in vitro, said method comprising contacting said cell with an isolated Yatapoxvirus cytokine inhibitor protein and the use of an isolated Yatapoxvirus cytokine inhibitor protein for the manufacture of a medicament for the treatment of an inflammatory or immune-mediated disease condition. |