http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1833788-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_970bfaebf93b450409d646017acb44b4 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42 |
| filingDate | 2005-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10c03ef89b5aee369036dd92409fcab4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_209b938522e0fdb6eeeb3f8f0275cf4c |
| publicationDate | 2007-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1833788-A1 |
| titleOfInvention | Process for preparing perindopril erbumine |
| abstract | The present invention relates to a new process for preparing perindopril erbumine (I), useful in the treatment of hypertension. The invention relates to obtaining 1-[(2S)-2-[[(1S)-1(ethoxycarbonyl)butyl]amino]-1-propionyl] (2S,3aS,7aS)-octahydro-1H-indole-2-carboxylic acid, tert-butylamine salt that comprises reacting an active ester of N-[2(S)-(ethoxycarbonyl)butyl]-L-alanine with an organic salt of perhydroindole-2-carboxylic acid, followed by the addition of t-butylamine and an acid to the reaction medium, in any order, or else a salt formed from an acid and tert-butylamine, and separating the product by conventional means. |
| priorityDate | 2004-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.