http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1831214-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2919a384e8471477b61879f48477938 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
filingDate | 2004-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95f8fba80a21bb29048da758af9b79b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0702ddb64040f1ce081f1693d803c00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1d1ddb88738e5d487da9f6a744d21d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_961bfd29c4c538596bc0e10cf748a6ba |
publicationDate | 2007-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1831214-A1 |
titleOfInvention | A process for preparation of 4-amino-1-isobutyl-1h-imidazo[4,5-c]-quinoline (imiquimod) |
abstract | A process for preparation of imiquimod comprising oxidation of 1-Isobutyl-1H-imidazo quinoline quinoline (II) afforded 1-Isobutyl-lH- imidazo-[4,5-c]-quinoline-5-N-oxide (III) which is isolated in pure form as its hydrochloride salt (IV) followed by conversion to 4-chloro derivative(V) and conversion to corresponding 4-iodo derivative (VI) which is a new intermediate. This new intermediate is convened to imiquimod (VIII) and purified via its novel maleate salt. |
priorityDate | 2004-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 127.