| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b5a8a82d02a54d7833c7e0c9b4289b6 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5513
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P23-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P23-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-00 |
| filingDate |
2005-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2fdef582639cc5c1dba171f7af2b731 |
| publicationDate |
2007-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1830856-A2 |
| titleOfInvention |
Preventing pathological increases in the rate of nerve cell suicide in immature nervous systems |
| abstract |
A method for preventing pediatric and obstetric medical drugs from triggering apoptotic neurodegeneration in an immature nervous system is disclosed. The method comprises coadministration of (1) a drug that has been shown in in vivo tests to trigger apoptotic neurodegeneration in unprotected neonatal mammals and (2) a drug the enters the mammalian central nervous system and stimulates neuronal activity to prevent neuroapoptosis. Examples of the first group of drugs include drugs that suppress activity at the NMDA subclass of glutamate receptors and promote inhibitory transmission through at least one class of GABA receptors. Examples of the second drug include, lithium and xenon. |
| priorityDate |
2004-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |