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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D275-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-04
filingDate 2005-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6639582aa8ab05114389eb1734640f1e
publicationDate 2007-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1829868-A1
titleOfInvention Process for production of (4,5-dihydroisoxazol-3-yl)thio- carboxamidine salts
abstract To provide a method for producing a (4,5-dihydroisoxazol-3-yl)thiocarboxamidine salt compound simply, safely and in good yield, whereby drawbacks of prior art have been solved. n A method for producing a (4,5-dihydroisoxazol-3-yl)thiocarboxamidine salt compound of the formula (2):n nwherein each of R 1 and R 2 which are independent of each other, is a hydrogen atom, an alkyl group or a cycloalkyl group, each of R 3 and R 4 which are independent of each other, is a hydrogen atom or an alkyl group, provided that R 1 and R 2 , or R 2 and R 3 , may be bonded to each other to form a cycloalkyl group together with the carbon atoms to which they are bonded, and X 2 is a halogen or an anionic residue derived from an acid, which comprises reacting a 3-halogeno-4,5-dihydroisoxazole compound of the formula (1) :n nwherein R 1 , R 2 , R 3 and R 4 are as defined above, and X 1 is a halogen, with thiourea in the presence of an acid.
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