abstract |
A process is described for the preparation of drospirenone, a synthetic steroid with progestogenic, antimineralocorticoid and antiandrogenic activity, useful for preparing pharmaceutical compositions with contraceptive action; comprising the oxidation of 17α-(3-hydroxypropyl)-6β, 7β, 15β, 16β-dimethylene-5β-androstane- 3β , 5, 17β -triol. |