http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1827445-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e911305f2cb02b43368a069a93d30519 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
| filingDate | 2005-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb7afd2991d09575da1341820672e896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_682dcaa67c58d91ce158516be0849310 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74f3eaa52ea55f510eb4cf9974782f9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42cb4b782310f8d98220f92ffacefbff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1be2516cf67d16467e04805b4f3b9e92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f936eb4f28888dd44e38cc98afd3618 |
| publicationDate | 2007-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1827445-A2 |
| titleOfInvention | Enhancing treatment of cancer and hif-1 mediated disoders with adenosine a3 receptor antagonists |
| abstract | The present invention relates to the use of adenosine receptor antagonists, preferably A3 receptor antagonists, either alone or in combination with other agents for the treatment, prevention and/or management of diseases or disorders associated with overexpression of HIF-lα and/or increased HIF-1 α activity (e.g., cancer, respiratory disease). The methods and compositions of the invention are particularly useful for preventing, treating, or ameliorating symptoms associated with a cancer, disease or disorder associated with hypoxia-inducible factor 1-α (HIF-lα) using the A3 receptor antagonists of the invention. The present invention provides methods to inhibit the growth of tumors, particularly solid tumors and more particularly hypoxic tumors. |
| priorityDate | 2004-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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