http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1817428-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39e489466bd46121bfe8a7a7f429e20b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6832 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6844 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2005-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdcc4d5ce23f5a68fe11bba6f5bd8372 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2595ac53e610dd38480d0f1e6dfa3c21 |
| publicationDate | 2007-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1817428-A1 |
| titleOfInvention | A method for increasing the specificity of enzymatic dna synthesis |
| abstract | The invention provides a method of performing a DNA polymerase reaction by including in a reaction mixture containing a DNA polymerase a compound of the formula (I): wherein: R1, R2, R3, R4, R5 may be the same or different and are independently selected from the group consisting of -H, -OH, -F, -Cl, -Br, -CF3, -CCl3, -CBr3, -NH2, -NO2, -CN, -CONH2, -CHO, -CO2H, -SH, -SO3H, -OPO3H2 and a group R7, R6 is selected from the group consisting of -O-, -OPO3H2, -CF3, -CCl3, -CBr3, -CN, -CONH2, -CHO, -CO2H, and a group R7; each group R7 is independently selected from C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, or an aryl or heteroaryl ring containing from 5 to 8 ring members, which in the case of heteroaryl rings may include 1 or 2 nitrogen, oxygen or sulphur atoms or mixtures thereof, the remainder being carbon, and wherein R7 is optionally be substituted by from 1 to 4 groups selected from -OH, -F, -Cl, -Br, -I, -CF3, -CCl3, -CBr3, -NH-NH2, , -NH2, -NO, -NO2, -CN, -CONH2, -CHO, -CO2H, -SH, -SO3H, -OPO3H2, or mixtures thereof, and further optionally R7 may comprise a group -NH-NH-, -NN-, -NH-, -CO-, -S-S-. Kits comprising a DNA polymerase and compounds of the formula (I) also form part of the invention. |
| priorityDate | 2004-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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