Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d21cbff64022f95c237c0bd3ec8656ca |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1641 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
filingDate |
2005-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_623cbbfb96ba1cdc38f5c506e336007b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4aa747c87a8e22b349ba7b5e56b1a995 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a9c0d8fe33c3eeb74bd340b71f2308a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9aee486d8098da7a1a4378ef532a7ad3 |
publicationDate |
2007-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1817008-A2 |
titleOfInvention |
Stabilized hme composition with small drug particles |
abstract |
A hot-melt extruded composition having finely divided drug-containing particles dispersed within a carrier is provided. The carrier melts during extrusion but does not dissolve the drug. As a result a majority of the particles are noπaggregated during extrusion into crystalline or amorphous particles. Various excipients can be included in the carrier system to stabilize the particle size. A hydrophilic polymer can also be Included in the composition. A process for preparing the extrudate Is conducted at a temperature at or above the melting point of the matrix and below the point of solubilization of the drug-containing particles and below the rβcrystallization point of the amorphous fine-drug particles. |
priorityDate |
2004-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |