http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1813619-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b1c7560aa50b0da1769cd5b6f735b69 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 |
filingDate | 2005-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3d858ec14dfab9ad7ab852793c3229e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4223896c774bc3aec7fa618c410a8b0d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6cca2d5b3af28381cd517cdecb6a061 |
publicationDate | 2007-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1813619-A1 |
titleOfInvention | Process for producing penam compound |
abstract | An object of the invention is to provide an industrially advantageous process capable of remarkably suppressing the generation of an undesirable by-product cepham compound to thereby efficiently produce a desired 2α-methyl-2β-[(1,2,3-triazol-1-yl)methyl]penam-3a-carboxylic acid ester. In the present invention, a diphenylmethyl 2β-bromomethyl-2α-methylpenam-3α-carboxylate (BMPB) is reacted with 1,2,3-triazole in a halogenated hydrocarbon solvent at -5°C or lower. The reaction in a halogenated hydrocarbon solvent at -5°C or less can remarkably suppress the generation of an undesirable by-product cepham compound, so that the desired diphenylmethyl 2α-methyl-2β-[(2,2,3-triazol-1-yl)methyl]penam-3α-carboxylate (TMPB) can be efficiently produced. |
priorityDate | 2004-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.