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filingDate 2005-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc5256aa019db5f75b8d083c9c3d9898
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e62b1cb2189c8bac0e5a2de7e1538320
publicationDate 2007-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1807187-A1
titleOfInvention Method for coating powders
abstract The invention concerns a method for coating powdery solid active substances characterized in that it comprises the following steps: a) providing (2; 3; 4) a mixture comprising at least one coating agent wherein is dissolved a supercritical or subcritical fluid in conditions of temperature and pressure enabling said fluid to be maintained in supercritical or subcritical conditions; b) providing (7) individualized moving particles of at least one powdery solid active substance; c) contacting (8) the mixture and the moving individualized particles of active substance in conditions of temperature and pressure ensuring simultaneously expansion of the supercritical or subcritical fluid and its restoration to gaseous state, the atomization of the coating agent and its solidification around the moving individualized particles of active substance; d) separating and recuperating the coated particles (9). The invention also concerns coated microparticles of active substance, each microparticle comprising successively a core containing the active substance and a shell containing the coating agent, characterized in that they are obtainable by the inventive method and in that the active substance is solid and heat-sensitive at room temperature, and in that the average size of the active substance core is less than 50 νm.
priorityDate 2004-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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