http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1802646-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ce7e5ae3b93c05abe32afc08089aabe |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4747 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate | 2005-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77831fd926a3bf04f37ca8dc78feff67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bac68d793cd429bcd643737b635b783b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64c0fa705af400bbde45270ca5d2a00d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8088b5684fecd438342b9c4bb17de51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a7382b05e094fbf0579913a1e94f7b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8383f2bb5cc3839063cec6db993656f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5c64fe29587cd89a5a24066a0cb8b4e |
| publicationDate | 2007-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1802646-A2 |
| titleOfInvention | Methods and compositions for increasing longevity and protein yield from a cell culture |
| abstract | Disclosed herein are compositions and methods for increasing the longevity of a cell culture and permitting the increased production of proteins, preferably recombinant proteins, such as antibodies, peptides, enzymes, growth factors, interleukins, interferons, hormones, and vaccines. By transfecting cells in culture with an apoptosis-inhibiting gene or vector, cells in culture can survive longer, resulting in extension of the state and yield of protein biosynthesis. Expression of the apoptosis-inhibitor within the cells, because it does not kill the cells, allows the cells, or an increased fraction thereof, to be maintained in culture for longer periods. This invention then allows for controlled, enhanced protein production of cell lines for commercial and research uses, particularly the enhanced production of growth factors, interferons, interleukins, hormones, enzymes, and monoclonal antibodies, and the like. The method preferentially involves eukaryotic cells in culture, and more advantageously mammalian cells in culture. |
| priorityDate | 2004-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 422.