http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1791846-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_35bce0b8363dc3e87c11597734a15083 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-58 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-58 |
filingDate | 2004-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a886b855f16031d041146bcdbbd9af68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_546c58a3bfc27947fb47cd9562ee6a16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc4a86bda5a04f438d96bda3f99bc2db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_569ca2465d40fc4cbe313b632cce0fb2 |
publicationDate | 2007-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1791846-A1 |
titleOfInvention | An improved process for the preparation of irinotecan hydrochloride trihydrate |
abstract | The invention relates to an improved process for the preparation of Irinotecan hydrochloride trihydrate of formula (4) of enhanced yield, purity by contacting 1-chlorocarbonyl-4-piperidinopiperidine hydrochloride with 7-ethyl-10 hydroxy-camptothecin [IRT-3 (synthetic)] to obtain crude Irinotecan which is subsequently purified by solvent treatment, obtaining purified irinotecan which is converted into irinotecan hydrochloride trihydrate and the invention also relates to a report of the compound 1-chlorocorbonyl-4-iperidinopiperidine hydrochloride of formula (1) and its process for preparation. |
priorityDate | 2004-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 94.