| abstract |
It has been found that compounds of formula (I)n nwherein, in preferred embodiments nX 1 and X 2 are N-H or N-R 3 or N-R 4 , nR N and R C are both H nR 1 and R 3 are independently from each other optionally substituted phenyl, or R 1 and R 2 and/or R 3 and R 4 form together with the N to which R2 and/or R 4 , respectively, are bound a 5 or 6 membered heterocycle comprising 1 or 2 heteroatoms, and nA is preferably halogen substituted phenyl or a preferably phenyl substituted furanyl nare good β-secretase inhibitors for the treatment of Alzheimer's disease. |