http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1789434-A2

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3120ae9cab5bb4831f0cc16288966367
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-113
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00
filingDate 2005-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46df95a868943f4b942fd23531a26c93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cac5d868e68958ca3e54447d493a53ef
publicationDate 2007-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1789434-A2
titleOfInvention Use of tris(hydroxymethyl) aminomethane for the stabilization of peptides, polypeptides and proteins
abstract The present invention is directed to a method for reducing the onset or incidence of gelation/fibrillation/aggregation during the up- and down-stream processing and purification of peptides, polypeptides and proteins analogs and/or derivatives thereof, including Glucagon-Like Peptides (GLPs). More particularly, the present invention relates to methods of processing and purifying such peptides, polypeptides and proteins in the presence of tris(hydroxymethyl)aminomethane.
priorityDate 2004-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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