Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_029116ee41eeec8a03f88a8cddbaa758 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-604 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L29-041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L29-16 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L29-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L29-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16 |
filingDate |
2005-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_813cd005260529389a62d3698b7cdd32 |
publicationDate |
2007-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1786487-A1 |
titleOfInvention |
Medical devices having self-forming rate-controlling barrier for drug release |
abstract |
Therapeutic-agent-releasing medical devices are provided herein, which contain a rate controlling release region that includes a biodisintegrable agent and a biostable low glass transition temperature polymer. Upon contact (e.g., implantation or insertion) of the medical device with a subject, at least the surface of the release region becomes depleted of the biodisintegrable agent, and the low glass transition temperature polymer migrates to occupy at least a portion of the volume that is created by the departure of the biodisintegrable agent, thereby forming a barrier layer for therapeutic agent remaining within the device. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10369256-B2 |
priorityDate |
2004-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |