Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2b03342511abc88f60c63f2acd96d0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4721 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 |
filingDate |
2005-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f0ecb898698526f0c19d98931bac0b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c717dc5a8cbca099fc19545d6af708c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_951f21daa78429a45174712632231b60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fce644910bb39a70aeb85f703995092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e68aff79c5cd46607d34a18eacdbabde |
publicationDate |
2007-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1784483-A2 |
titleOfInvention |
Peptide sequence for modulation of delta protein kinase c |
abstract |
A peptide identified from the annexin V protein sequence and having the ability to modulate the activity of delta protein kinase C (PKC) is described. The peptide and variants thereof bind to delta PKC and are effective to regulate delta PKC mediated cellular responses. In particular the annexin V peptide is able to inhibit protein-protein interaction with delta PKC, blocking intracellular translocation of delta PKC. Inhibition of delta PKC translocation confers protection to tissue at risk of exposure to ischemia or hypoxia or to reperfusion injury. |
priorityDate |
2004-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |