Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3120ae9cab5bb4831f0cc16288966367 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
filingDate |
2004-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55727b1688f6551096824052fff6807d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b4c24836652e360c399d56ec5caa051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a50f35fa7f55ed48faf4717f69a0000e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a4770a91eaaf7ac5445c1cbc6d454b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_458bb0ca1c4004e6f7364c262f5edff8 |
publicationDate |
2007-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1782859-A2 |
titleOfInvention |
Pharmaceutical use of substituted pyrazolo [1,5- a]pyrimidines |
abstract |
The use of substituted pyrazolo[1,5- a ]pyrimidines for modulating the activity of 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) and the use of these compounds as pharmaceutical compositions are described. Also a novel class of substituted pyrazolo[1,5- a ]pyrimidines their use in therapy, pharmaceutical compositions comprising the compounds, as well as their use in the manufacture of medicaments are described The present compounds are modulators and more specifically inhibitors of the activity of 11βHSD1 and may be useful in the treatment, prevention and/or prophylaxis of a range of medical disorders where a decreased intracellular concentration of active glucocorticoid is desirable. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008116601-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008116601-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-020331-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1972335-A1 |
priorityDate |
2003-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |