http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1777297-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4625ca7b4dbee128c88cd85dfc84f896 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65522 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-09 |
| filingDate | 2004-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90166a38255bc16c2a39e563c89a0f41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c0d8f2c293a7a6f5ab784deb9d5e7d2 |
| publicationDate | 2007-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1777297-A1 |
| titleOfInvention | Fluorescent substrates for detecting organophosphatase enzyme activity |
| abstract | Compounds of the formula I:n nwherein nR 3 is selected from the group consisting of H, cyano, C 1 -C 6 alkyl, C 1 -C 6 perfluoroalkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, aryl, and heteroaryl, formyl, carboxamide of the formula -(C=O)NR 1 R 2 where R 1 and R 2 are independently H, alkyl having 1-6 carbon atoms, an aryl, or R 1 and R 2 taken together form a saturated 5- or 6- membered ring having the formula -(CH 2 ) 2 -M-(CH 2 ) 2 - where the ring moiety M is a single bond, an oxygen atom, a methylene group, or the secondary amine -NR 7 - where R 7 is H or alkyl having 1-6 carbon atoms; nR 4 is selected from the group consisting of H, hydroxyl, cyano, nitro, halo, amino, amido, azido, acetal, ketal, imido, sulfo, sulfonyl, sulfinyl, sulfomethyl, salt of sulfomethyl, thiocyanato, aldehydo, keto, carbamoyl, urethane, ureido, guanidino, C 1 -C 6 alkylamino, C 1 -C 6 acylamino, C 1 -C 6 alkylamido, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 6 perfluoroalkyl, halomethyl, C 1 -C 6 alkylthio, C 5 -C 8 cycloalkyl, C 1 -C 6 haloalkyl, C 5 -C 8 halocycloalkyl, C 1 -C 6 hydroxyalkyl, C 5 -C 8 hydroxycycloalkyl, C 1 -C 6 alkoxy C 1 -C 6 alkyl, C 2 -C 6 alkoxycarbonyl, C 2 -C 6 alkoxycarbonyl C 1 -C 6 alkyl, carboxy C 1 -C 6 alkyl, carboxy C 1 -C 6 alkoxy, dicarboxy C 1 -C 6 alkyl, dicarboxy C 1 -C 6 alkoxy, C 2 -C 6 cyanoalkyl, phosphono C 1 -C 6 alkyl, phosphoryl C 1 -C 6 alkyl, mono-, di-, and trisaccharides, nucleic acids, oligonucleotides, amino acids, peptides, and proteins, and C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, aryl, arylcarbonyl, and heteroaryl, which may be optionally substituted with a substituent selected from the group consisting of hydroxyl, cyano, nitro, halo, amino, amido, azido, acetal, ketal, imido, sulfo, sulfonyl, sulfinyl, thiocyanato, aldehydo, keto, carbamoyl, urethane, ureido, and guanidine; nR 5 is H or C 1 -C 6 alkoxy; nR 9 and R 10 are ethyl; nR 6 and R 8 are halo; and nX 1 , X 2 , and X 3 are independently O or S. |
| priorityDate | 2003-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 290.