http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1771579-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c6946793401973ea6d2418351f8720e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
| filingDate | 2005-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0831d547805ec7606a58e737027438a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c2b0c157332f6cf80b60b54fcbf65b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_506a7f7ce85cc3ad434c363b3cd1205d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87245b1f343ce775e0c99cec7247d718 |
| publicationDate | 2007-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1771579-A2 |
| titleOfInvention | Design, synthesis and assembly of synthetic nucleic acids |
| abstract | Methods of synthesizing oligonucleotides with high coupling efficiency (>99.5%) are provided. Methods for purification of synthetic oligonucleotides are also provided. Instrumentation configurations for oligonucleotide synthesis are also provided. Methods of designing and synthesizing polynucleotides are also provided. Polynucleotide design is optimized for subsequent assembly from shorter oligonucleotides. Modifications of phosphoramidite chemistry to improve the subsequent assembly of polynucleotides are provided. The design process also incorporates codon biases into polynucleotides that favor expression in defined hosts. Design and assembly methods are also provided for the efficient synthesis of sets of polynucleotide variants. Software to automate the design and assembly process is also provided. |
| priorityDate | 2004-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1311.