abstract |
Certain non-imidazole heterocyclic compounds of formula (I) are histamine H3 modulators useful in the treatment of histamine H3 receptor mediated diseases, wherein in the A- and B-containing ring, I) A, B1 and B2 are CH; II) A is CH, one of B1 and B2 is N, and the other of B1 and B2 is CH; or III) A is absent, B1 is CH, and B2 is O; L is -C1-4alkylene- or a covalent bond; Q is -(CH2)mO-, -(CH2)nC=C-(where the -O- and -C=C-portions are directly attached to the ring), carbonyl, or thiocarbonyl; m I 2, 3, or 4; n is 1, 2, 3, or 4. |