| abstract |
Sensor constructs 10 for detecting the presence of an analyte 60 in a sample comprise a molecular scaffold 20, a pair of labels 40, 50 which interact via Förster resonance energy transfer, and at least one molecular recognition domain 30. When the analyte 60 is bound by the molecular recognition domain 30, the Förster resonance energy interaction between the pair of labels 40, 50 is disrupted, resulting in a changed optical signal. |