http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1748760-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e933190d60518518d41492f5e613876e |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
filingDate | 2005-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_638ae648ab5519eb9bfe69fc6a7b7d9f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d24233b1d7a52e162b5605785b0403a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c49fcbb3c6c1e50e2e330786c8da275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_027641e8f85a8a9e2190d9b218e33261 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_faba3f26626dc6b983aeaf11c1eb4b86 |
publicationDate | 2007-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1748760-A1 |
titleOfInvention | Superloaded liposomes for drug delivery |
abstract | The present invention relates to liposomes for drug delivery, wherein a liposome comprises molecules of at least one desired drug distributed within an aqueous phase in the interior of the liposome and wherein the liposome further comprises molecules of the same or of another drug attached to either or both sides of the liposomal membrane. More specifically, the invention relates to liposomes, wherein at least a part of the molecules of a desired drug bear a functional group that is reactive with a functional group present in at least one lipid fraction, and wherein the drug is covalently linked to the membrane lipids by chemical bonding, e.g. by ester bonding of a hydroxyl group of a lipid molecule and an acidic residue of the drug. In a preferred embodiment, the desired drug is a glycoprotein such as erythropoietin. The invention further relates to a method of manufacture of said liposomes and to pharmaceutical compositions containing them. |
priorityDate | 2004-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 147.