http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1748297-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e3750e3a4c24155bb7b01636dc33e7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_676276fa89cd6f0239e6aaf1353244b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5e7a9f9b6aa26ac3a15dfb7b4c82bc2 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6863 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2006-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f7e0b894e21c49887afa435e82e8cf2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32571847a04e425f1a9913b25f5959b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3aa3f96848eaa0df7a006c6e7f3b2f2c |
publicationDate | 2007-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1748297-A1 |
titleOfInvention | Method for analysing naturally occuring peptides and small proteins using mass spectrometry |
abstract | One method was developed for the separation and identification of the naturally occurring peptides and small proteins (NOP/SP) present in biological fluids with the use of mass spectrometry. The separation of protein molecules with molecular weight <10kDa is achieved through mixing of one volume of the biological fluid with 7 to 9 volumes of aqueous solution containing 50% acetonitrile and 0.1% trifluoroacetic acid (TFA). As opposed to the methods currently used, the present method does not include complicated and time consuming steps (fractionation, chromatography, ultrafiltration, etc.). Because of the NOP/SP analysis with MALDI-TOF the method is rapid, subject to automation and quantification. These elements constitute the method as highthrouput and appropriate for pathological states diagnosis, either through analysis of one or more NOP/SPs as specific biological markers, or through comparison of normal and pathological patterns/profiles. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112067728-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112067728-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113527459-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111707756-A |
priorityDate | 2005-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.