http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1747287-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07d04c30739c1a97585f0fa306ad3d23 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2005-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5771227655a5ec8bbe1778014b5b29b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b038544d4a1a1a9efc461a3ea2ffd7ae |
| publicationDate | 2007-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1747287-A2 |
| titleOfInvention | Genotoxic testing |
| abstract | The present invention relates to methods for detecting for the presence of an agent that putatively causes or potentiates DNA damage comprising subjecting a cell (containing a DNA sequence encoding a reporter protein operatively linked to a human GADD45α gene promoter and a human GADD45α gene regulatory element arranged to activate expression of the DNA sequence in response to DNA damage) to an agent; and monitoring the expression of the reporter protein from the cell. The invention also concerns expression cassettes, vectors and cells which may be used according to such a method and also modified media that may be employed in fluorscence assays and in preferred embodiments of the method of the invention. |
| priorityDate | 2004-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 154.