http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1744785-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f4fc0d3206a5e2c997c11d60e92e0b75 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-54 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
filingDate | 2004-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b936ffd50a6c3e81b8fdae1bfb654fef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb3087f4c7f822ffba8e63399fa64f51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5953c860f50c9de011bbb4d3fe0948a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ecfa92db035436a06ba020009a0d965 |
publicationDate | 2007-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1744785-A1 |
titleOfInvention | Hydroxyalkyl derivatives of biologically active compounds |
abstract | Hydroxyalkyl derivatives of biologically active compounds represented by the formula VII wherein R2 = H, CI-12 alkyl, C6-12 aryl, or -OH and D = Biologically active agent having functional groups such as Formula (a) epoxy or aziridine and Z' = Formula (b) L= spacer comprising (un)substituted alkyl, hydroxyalkyl or alkoxy alkyl with the condition that the carbon chain length contains 2 to 6 carbon atoms when Z' = Formula (c) and pharmaceutically acceptable acid addition salts and enantiomers thereof Also process for the synthesis of compounds of the Formula VII and pharmaceutically acceptable acid addition salts and enantiomers thereof comprising condensation of the biologically active agents having functional groups such as Formula (d) epoxy or azifidine with substituted alkyl derivatives under alkaline conditions, at 20 - 80°C, in an organic solvent. |
priorityDate | 2004-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 542.