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filingDate 2004-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51e03decb1abe1959aef56489ddeed15
publicationDate 2007-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1737975-A2
titleOfInvention Methods to identify evolutionarily significant changes in polynucleotide and polypeptide sequences in prokaryotes
abstract Methods for identifying polynucleotide and polypeptide sequences which may be associated with commercially relevant or useful traits in prokaryotes are provided. The methods employ comparison of homologous genes from two closely related prokaryote species to identify evolutionarily significant changes. Sequences thus identified may be useful in developing therapeutics, diagnostics, or vaccines.
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