| abstract |
A novel anti-itching agent useful for the treatment of itches accompanying various diseases. The anti-itching agent contains as an active ingredient a morphinan derivative having a specific nitrogenous cyclic substituent or a pharmacologically acceptable acid addition salt thereof, such as, e.g., N-(17-cyclopropylmethyl-4,5α-epoxy-3,14-dihydroxymorphinan-6β-yl)phthalimide hydrochloride, [Chemical formula 1] (1) or N-(17-cyclopropylmethyl-4,5α-epoxy-3,14-dihydroxymorphinan-6β-yl)-3,4,5,6-tetrahydrophthalimide tartrate. |