http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1734130-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac76f174dc30cc5514dccc90b04c6d8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec5b8c0fc1f827c1360a8f5ea5652225 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_adb0e564374fedf34b36103d36e6455a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-42 |
| filingDate | 2005-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_847f3d05fc9e7aefd8617a58bf040b0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc48321e1289fc9d4cb43ca0c4ff5a96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdcd127195553be8276befe4a6951509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2280fcbc927af8ba42d8756f4bbb1b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ede4f65949b89cfc9e3e07504e14213 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a5afae4f433653ac3c0bbed010cc9e0 |
| publicationDate | 2006-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1734130-A1 |
| titleOfInvention | Improved biosynthetic production of 2,3-trans-CHD |
| abstract | The invention relates to a process for the biosynthetic production of [5 S ,6 S ]-5,6-dihydroxy-cyclohexa-1,3-diene-1-carboxylic acid (2,3- trans -CHD) in an Escherichia microorganism having increased activity of isochorismate synthase and isochorismatase, and being deficient in activity of 2,3-dihydroxybenzoate synthase, wherein the process is carried out in a chorismate overproducing host microorganism also having decreased glucose dehydrogenase activity. In this improved biosynthetic process, 2,3- trans -CHD is being produced in high yields and at concentrations in the biosynthetic reaction medium of at least 12 g/l. n The invention further relates to the use of the supernatant of a process for the biosynthetic production of [5S,6S]-5,6-dihydroxy-cyclohexa-1,3-diene-1-carboxylic acid (2,3-trans-CHD) where the concentration of 2,3- trans -CHD in the process has arrived at a concentration of at least 12 g/l as a source for a co-factor for PQQ dependent enzymes. |
| priorityDate | 2005-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 666.