| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate |
2005-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7480dd2f668d85c56a1152bb1254f8e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ee4a255c18637ad0d404bd47bee212c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1723a87adbb93e91b2cbc452e45ecde3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67fe49569934f5f90ff45040d672e25f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58a995730c4e43ae49fd5dffd07324b9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c384e8c5e84dbbadc85d5fb5697f093c |
| publicationDate |
2006-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1733051-A2 |
| titleOfInvention |
Method and biomarkers for detecting tumor endothelial cell proliferation |
| abstract |
Methods, biomarkers and expression signatures are disclosed for assessing the proliferative rate of vascular endothelial cells. More specifically, the invention provides a set of genes which can be used as biomarkers and gene signatures for evaluating the pharmacodynamic effects of cancer therapies designed to regulate the proliferation of endothelial cells in tumor vasculature. In one aspect the invention provides a method of evaluating the efficacy of a compounds designed to inhibit kinase receptor activity, such as a mammalian KDR receptor activity. |
| priorityDate |
2004-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |