| abstract |
The present invention provides a compound represented by the following Formula:n nwherein A is an aryl group or a heteroaryl group, each of which may be substituted; R 1 is a group which is bonded through carbon; R 2 is hydrogen or an aliphatic hydrocarbon group; and X is -NR 3 -, -O-, -S-, -SO-, -SO 2 -, or -CHR 3 -(wherein R 3 is hydrogen or an aliphatic hydrocarbon group), or a salt thereof, or a prodrug thereof, which has growth factor receptor tyrosine kinase inhibitory activity and low toxicity, and is useful for prevention and treatment of cancer, and thus can be sufficiently used as a medicine. |