Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f84747e8d08b1023763356d0e7d1db68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d0446a5bd77c7da68216fc2e3f05d48 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-807 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
filingDate |
2005-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afc3002a3809025ee7530f8a40684c1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74192c5afd7f66e199cc323bf697b5e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_537f4cfb1541b84d7353d92666844f01 |
publicationDate |
2006-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1730171-A1 |
titleOfInvention |
Peptide mimotopes of mycobacterial mannosylated lipoglycans and uses thereof |
abstract |
The present invention relates to the identification of antigenic and immunogenic peptide-based mimicry of mannose-containing cell-wall compounds characterizing mycobacterial infectious agents, such as Mycobacterium tuberculosis. Thus, the present invention provides amino acid molecules which are mimotopes of mannosylated lipoglycans, such as lipoarabinomannan (ManLAM), comprising at least one of the following characteristics: (a) being capable of binding to ManLAM binding antibodies; (b) being capable of eliciting production of ManLAM binding antibodies. The amino acid of the invention is used in a diagnostic method for diagnosing mycobacterial infections and in a method of vaccinating subject against such infections. Accordingly, the invention also provides a diagnostic kit and a vaccine for the executing the aforementioned methods. |
priorityDate |
2004-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |