| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_632b8460805536fc8ff035a407817c4c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2203-0282 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N3-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2005-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3071e468d1ffe89cd1eba6cc2c651d96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f3e2416d7482c81f7181bd2cb55684d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0462f295f7c7085092212ea865c091f |
| publicationDate |
2006-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1729132-A1 |
| titleOfInvention |
Method of detecting amyloid structural change in protein, method of searching for substance having activity of affecting amyloid structural change and method of searching for remedy or diagnostic for amyloid-related disease |
| abstract |
The inventors investigated to provide a means for real-time detection and measurement on the process of the amyloid protein aggregation as change(s) in tension and/or elasticity using a force sensor. The present invention provided a method of detecting an amyloidgenic conformational change of a protein using a mechanochemical sensor. The present invention further provided a method of searching a substance having an activity that affects to an amyloidgenic conformational change using said detecting method, as well as a method of searching a therapeutic or diagnostic agent for amyloid-related diseases. The method of the present invention is assumed to contribute to obtain a novel therapeutic or diagnostic agent for amyloid diseases. |
| priorityDate |
2004-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |