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filingDate 2005-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_831ee510afceed29f546c8766e9bd53d
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publicationDate 2008-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1724251-A4
titleOfInvention PROCESS FOR THE PRODUCTION OF OPTICALLY ACTIVE HYDROXYMETHYL COMPOUNDS
abstract [PROBLEMS] To provide catalysts permitting the progress of asymmetric hydroxymethylation with high asymmetric selectivity and processes for the production of optically active hydroxymethylated compounds with the catalysts. [MEANS FOR SOLVING PROBLEMS] Use of a catalyst obtained by mixing a chiral ligand (such as compound 4) with scandium triflate or the like in the reaction of silicon enolate with formaldehyde brings about optically active hydroxymethylated compounds with high asymmetric selectivity.
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