Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dce748195aba2abde4a45e0c7a72b7f5 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-58 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 |
filingDate |
2005-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99e31fbcf3ab0079378a9d1a4f06459c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_213cc77f6d56575ef5f9e56366cebbc1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c7a4edcbce043e2562ed5164a2067ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17270632ffdd6b329cb1307ea633c56e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53c2d7586fafd80ceef92d00e20a0da7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0e116f0b05faa4b0ae62cedca4d0d2f |
publicationDate |
2006-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1723230-A1 |
titleOfInvention |
Altered expression in filamentous fungi |
abstract |
Agaricus bisporus serine protease is selectively expressed in the stipe, with maximum expression observed after 5 days at 18 °C, the promoter thereof being effective to permit selective expression of a heterologous protein in the fruiting body. Transformants can be selected without having to induce fruiting, by forcing expression using humic proteins. Post-transcriptional gene suppression is useful to suppress the serine protease to allow harvesting of heterologous proteins from the fruiting body without degradation by the serine protease. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113403209-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113403209-A |
priorityDate |
2004-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |