Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76a4701c8636c6a7a16ca4612510c33d |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-87 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-87 |
filingDate |
2004-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0479db9ed7071fcca13e8f103e35dfa9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7522d53afc2d92661ca0c2f1999a717d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05c701037b7094bd15ff551b808d1f17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdf91ddfc255845855e65ad2716ed8fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c87060adeddab20e040514855f67c7c |
publicationDate |
2006-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1723133-A1 |
titleOfInvention |
One pot synthesis of citalopram from 5-cyanophthalide |
abstract |
A process for one pot synthesis of citalopram is disclosed. The process comprises subjecting 5-cyano phthalide to Grignard reduction followed cyclization and followed by C-alkylation reaction to obtain citalopram without isolation and purification of any intermediates. In another embodiment, 5-cyano phthalide is subjected to sequential Grignard reactions followed by cyclization to obtain citalopram without isolation and purification of any intermediate stages. |
priorityDate |
2004-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |