http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1720851-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_86ea3a16f0dde635b49e6fd154d1c35a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-54 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-54 |
| filingDate | 2004-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1821348a12986f58512159495afc9bd4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b10022557b11e680b211569f33d97ce8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3fa9ae07b658b86deb3c440640e0391 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2785a639077797cad02c538671b453bb |
| publicationDate | 2009-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1720851-B1 |
| titleOfInvention | Process for synthesising heliotropine and its derivatives |
| abstract | A new high-yield, easily industrialized process for synthesising compounds of formula (IV), in which X1 and X2, the same or different, are linear or branched C1-C8 alkyls, n and m are 0,1 or 2, with the proviso that n and m are not simultaneously 0; or (OX1)n and (OX2)m taken together form an O-T-O group where T is chosen from -CH2-, -CH2CH2, -CH2CH2CH2-, -C(CH3)2-. The process comprises treating a chloromethyl derivative (I) with an alkaline acetate to form the intermediate acetylderivative (II); the intermediate (II) is to hydrolysed to form the alcohol (III); the alcohol (III) is then oxidised in the presence of air and catalysts to obtain the desired derivative (IV). The process runs its course within a short period of time, with high yields and high selectivity; in addition, the process does not require purification and separation of the intermediates and can therefore be favourably conducted in a single batch. |
| priorityDate | 2003-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.