http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1716847-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e66dcd041b390d50bd6668a9009a1e6f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1647 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-09 |
filingDate | 2006-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d00f0c3ab62f6d9273b77f8efcd32903 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff3b6db836ca80642406a79af050d1c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c41b2f51cea52fba3c47811f2a506502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d3e026915eb67403beafccfce9e88a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1204476365fefce34725ad12495e05c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86811f4a6ecad3cceb7d2673d2bffa30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54249edef1d44845f089f68f681f35ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9eee4ac0b6d19fc2ea71934accf86a25 |
publicationDate | 2006-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1716847-A1 |
titleOfInvention | Bioabsorbable pharmaceutical formulation comprising a PLGA copolymer |
abstract | An object of the present invention is to provide a bioabsorbable release-sustaining pharmaceutical formulation using a biodegradable release-sustaining base material which can prevent an effective component drug from being released too rapidly just after administration of the formulation and then allow continued release of the drug for at least one month at a defined rate, is provided. For the biodegradable release-sustaining base material, a lactic acid-glycolic acid copolymer (PLGA) with an adjusted distribution in molecular weight is used. For the biodegradable release-sustaining base material, a lactic acid-glycolic acid copolymer (PLGA) with an adjusted distribution in molecular weight is used. Specifically, the pharmaceutical formulation comprises the drug and the lactic acid-glycolic acid copolymer which has following fraction contents for their respective molecular weights determined by gel-permeation chromatography: a fraction content of less than 5% for a molecular weight of 40,000 or more, a fraction content of less than 20% for a molecular weight of 16,000 or more and less than 40,000, a fraction content of 45% or more for a molecular weight of 5,000 or more and less than 16,000, a fraction content of less than 10% for a molecular weight of 2,000 or more and less than 4,000, and a fraction content of 5% or more for a molecular weight of 500 or more and less than 1,500. |
priorityDate | 2005-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.