abstract |
To provide an intimal hyperplasia inhibitor useful for prevention of restenosis after percutaneous transluminal coronary angioplasty (PTCA) or vascular stent placement or treatment of its progress. n An intimal hyperplasia inhibitor containing a 3(2H)-pyridazinone compound represented by the formula (I):n n[wherein each of R 1 , R 2 and R 3 is independently a hydrogen atom or a C 1-6 alkyl group, X is a halogen atom, cyano or a hydrogen atom, Y is a halogen atom, trifluoromethyl or a hydrogen atom, and A is a C 1-8 alkylene which may be substituted with a hydroxyl group] or a pharmacologically acceptable salt thereof. |