http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1709439-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1cded1dd9dcc9dac6c1d9e44d8c1f78f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-463 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-461 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-24 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-7233 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-46 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72 |
| filingDate | 2005-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d6078c41b971e157cdc9c19594ba55e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b57b127d30a4df22233e463bbb2a7cd |
| publicationDate | 2006-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1709439-A1 |
| titleOfInvention | Method and system for reducing total sample complexity |
| abstract | A method for reducing total sample complexity in native or digested biological sample(s), before analysis thereof by mass spectrometry, comprising the following steps: a) selecting a fraction from the entire native or digested biological sample(s) on the basis of pI-value, said fraction comprising native or digested sample representing a subset of or the entire substance population in the sample, said fraction being obtained by e.g. anion exchange chromatography, isoelectric focussing or chromatofocussing; b) separating native or digested sample substances from each other, wherein said separation is by cation exchange chromatography; and c) analysing aid substances by mass spectrometry. The invention also relates to a system for reducing total sample complexity in the above method, comprising a high capacity charge-selective column (anion exchange, isoelectric focussing or chromatofocussing) coupled to a MDLC work flow path comprising a cation exchange column and a RPC column. The system is followed by a MS/MS instrument. |
| priorityDate | 2004-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 186.