abstract |
A catalyst composition for a cross-coupling reaction comprising a nickel salt-amine complex of formula (1), and triphenylphosphine.n nwhere R 1 thru R 4 independently represent alkyl, aryl, heteroaryl or alkanyl; n is an integer of 1-6 ; and X independently represents halo, hydroxyl, nitrate or acetate group. Using the catalyst composition, a cross-coupling reaction is carried out between a boron-containing compound of formula (2) and a compound of formula (3).n nwhere R 5 and R 6 are the same as R 1 -R 4 defined above; Y independently represents hydroxyl or alkoxy, Z is halo, methane sulfonate or trifluoromethanesulfonate. |