Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66c1b22707b0276e3078713a6ddcba91 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16122 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-11 |
filingDate |
2004-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf68e11c160045447820d7c3ff5ef82c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f8bb6dd6f106ca66b2050b5e5c58f70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd183c69303586d32dda9fb1b5d91842 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9575d76d5b5732f5605bef95c6c5946 |
publicationDate |
2011-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1704167-B1 |
titleOfInvention |
A method to make a peptide-carrier conjugate with a high immunogenicity |
abstract |
The present invention provides a method for making a peptide-carrier conjugate. The method comprises modifying a first peptide to produce a second peptide so that the pI of the second peptide is in a favorable range or closer to the range than the pI of the first peptide, and conjugating a plurality of the second peptide to OMPC to obtain a peptide-carrier conjugate. The peptide load, or the solubility of the conjugate, or both of them are increased by the modification. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9107906-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11780906-B2 |
priorityDate |
2003-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |