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filingDate 2004-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2006-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1697536-A2
titleOfInvention Novel oligonucleotides and treating cardiac disorders by using the same
abstract Novel oligonucleotides and methods of treating a cardiac disease or disorder using the same are provided. The oligonucleotides are useful in modulating the expression of the connexin 43 protein and may be combined with other biologically active agents and compositions to treat cardiac disease. Methods of modulating connexin expression include the suppression of the expression of connexin 43 and the inducement of expression of connexin 45.
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