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publicationDate 2006-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1697396-A2
titleOfInvention Mrna transfected antigen presenting cells
abstract A method of amplifying RNA to obtain RNA molecules that are predominantly in the sense orientation and essentially devoid of RNA molecules that are in the anti-sense orientation. A method of transfecting antigen presenting cells with a composition comprising sense RNA encoding immunogenic antigens and essentially devoid of antisense RNA and dsRNA is also provided as well as dendritic cells prepared according to the method.
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