http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1697383-A4
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8fb1456312aa7998c552f43f015e6bc |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-18 |
filingDate | 2003-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b94a2470aad368a594c0694e18b7356 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76b0c50676373987ef2a2d4586bb7c64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7e0e7950b2817a135de527487e9d74f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a04f8102ec3682909fa607d4ad314c7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bd25780b5711e5abde0d1d683260e07 |
publicationDate | 2008-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1697383-A4 |
titleOfInvention | PROCESS FOR PURIFYING MACROLIDES |
abstract | Process for the recovery of a macrolide in substantially pure form comprising: a) treatment of an impure or crude macrolide with water immiscible solvent, b) optional concentration of the mixture, c) treatment with ammonia gas to phase out impurities, d) separation of impurities, d) optional concentration of the phase containing the macrolide, f) loading on silica gel chromatography, optionally reversed phase or pretreated with silver, and elution of the macrolide, g) affording the macrolide in substantially pure form, h) optional repetition of step f) and g) to afford the macrolide in substantially pure form. The macrolide is preferably tacrolimus, immunomycin or sirolimus. |
priorityDate | 2003-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.